Organic Synthesis Bai. Zheng wu
Organic Synthesis Bai, Zheng Wu
Part I Introduction 1. The development history of organic synthesis 2. The influences of organic synthesis on organic chemistry 3. The research scope of organic synthesis
Part I Introduction 1. The development history of organic synthesis 2. The influences of organic synthesis on organic chemistry 3. The research scope of organic synthesis
Partl Introduction a Find new reactions b Synthesize new compounds with special functions C. Research on natural products
a. Find new reactions b. Synthesize new compounds with special functions c. Research on natural products Part I Introduction
4. Development trends of organic synthesis a Chiral synthesis (stereo-chemistry in reactions) b. Bio-catalytically organic synthesis C. Utilization of special methods in organic synthesis
4. Development trends of organic synthesis a. Chiral synthesis (stereo-chemistry in reactions) b. Bio-catalytically organic synthesis c. Utilization of special methods in organic synthesis
Part l Basic reactions
Part II Basic reactions
Oxidation reaction 1. Oxidation of side chain of aromatic compounds CH3 COOH KMno H
Oxidation reaction 1. Oxidation of side chain of aromatic compounds CH3 COOH KMnO4 H +
CH H3C—C—CH3 KMnO H Frequently used oxidants KMnO4, K2 Cr2O, O3/Zn, O3 O. Ch3COOOH
Frequently used oxidants: C CH3 CH3 H3 C KMnO4 H + KMnO4, K2 Cr 2 O7, O3/Zn, O3, O2, CH3 COOOH
2. Oxidation of aromatic compounds 02 V205
2. Oxidation of aromatic compounds O2 V2O5 O O O
Reduction reaction 1. Hydrogenation(氢化)
Reduction reaction 1. Hydrogenation (氢化)
3. Oxidation of olefins C-C O C=0+O-C O C O C HO oH OI C
3. Oxidation of olefins C C [O] C O + O C C C [O] C C O C C [O] C C HO OH
