Chapter 9 Motor System -1 Muscle contraction and motor unit
Chapter 9 Motor System - 1 Muscle Contraction and Motor Unit
Content Skeletal muscle contraction · Motor unit
Content • Skeletal Muscle Contraction • Motor Unit
Reference -Text Book DY5TESO7n ①…+:· 的二 GUYTON AND HALL Textbook of The Nervous System Medical Physiology secoND eDmoN 生理学 Aum Mdmek-Ttbe Puros Reves 3酯 E EDUCA HALL SAUNDERS P160-163 P71-82 UNIT XI The Nervous System: C P482-483 Motor and Integrative Neurophysiology
Reference – Text Book P160-163 P71– 82 P482-483 UNIT XI The Nervous System: C. Motor and Integrative Neurophysiology
Section i skeletal muscle contraction Signal Transmission Through Neuromuscular Junction Molecular mechanism of muscle Contraction Factors that affect the efficiency of muscle Contraction
Section I Skeletal Muscle Contraction • Signal Transmission Through Neuromuscular Junction • Molecular Mechanism of Muscle Contraction • Factors that Affect the Efficiency of Muscle Contraction
Part l Signal Transmission Through the Neuromuscular junction
Part I Signal Transmission Through the Neuromuscular Junction
Skeletal muscle innervation Path of action neuron Neuromuscular Axon junction e Motor end plate Supporting cell Synaptic terminal Sarcolemma Mitochondrion Myofibril Muscle b
6 Skeletal Muscle Innervation
Illustration of the neuromuscular Junction(NMJ Motor neuron fiber Nerve fiber branches Muscle fiber nucleus Motor end plate Myofibril of muscle fiber m e Mitochondria Synaptic vesicles Synaptic cleft Folded sarcolemma Motor end plate
7 Illustration of the Neuromuscular Junction (NMJ)
New lon Channel Players Voltage-gated ca2+ channel >in presynaptic nerve terminal >mediates neurotransmitter release P Nicotinic Acetylcholine receptor channel >in muscle neuromuscular junction (postsynaptic membrane or end plate) >mediates electrical transmission from nerve to muscle Nerve fiber branches Muscle fiber nucleus Motor end plate Myofibril of muscle fiber Motor end plate
8 New Ion Channel Players ➢Voltage-gated Ca2+ channel ➢in presynaptic nerve terminal ➢mediates neurotransmitter release ➢Nicotinic Acetylcholine Receptor Channel ➢in muscle neuromuscular junction (postsynaptic membrane, or end plate) ➢mediates electrical transmission from nerve to muscle
Neuromuscular transmission Axon Axon terminal Skeletal Muscle
9 Neuromuscular Transmission Skeletal Muscle Axon Axon Terminal
Depolarization Neuromuscular Nerve出i Transmission opens ca nnels potential invades Step by step axon terminal Look here
10 Neuromuscular Transmission: Step by Step Nerve action potential invades axon terminal - + - - - - - - + + + + + + + - - - + + Depolarization of terminal opens Ca channels Look here + +