Welcome each of you to My Molecular Biology class 博来字 Wuhan University
Welcome Each of You to My Molecular Biology Class
Molecular Biology of the Gene 5/E --Watson et al. (2004) Part I: Chemistry and Genetics Part: maintenance of the genome Part I: Expression of the Genome Part IV: Regulation Part v: methods
Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part I: Chemistry and Genetics Part II: Maintenance of the Genome Part III: Expression of the Genome Part IV: Regulation Part V: Methods
Part ll: Maintenance of the genome edicated to the structure of DNA and the processes that propagate, maintain and alter it from one cell generation to the next Wuhan universit
Part II: Maintenance of the Genome Dedicated to the structure of DNA and the processes that propagate, maintain and alter it from one cell generation to the next
Ch 6: The structures of dna and rna Ch 7: Chromosomes, chromatins and I the nucleosome Ch 8: The replication of DNA Ch 9: The mutability and repair of DNA Ch 10: Homologous recombination at the molecular level Ch 11: Site-specific recombination and transposition of DNA Wuhan University
Ch 6: The structures of DNA and RNA Ch 7: Chromosomes, chromatins and the nucleosome Ch 8: The replication of DNA Ch 9: The mutability and repair of DNA Ch 10: Homologous recombination at the molecular level Ch 11: Site-specific recombination and transposition of DNA
Molecular iology Course Chapter 11 Site-Specific Recombination Transposition of DNA 博来字 Wuhan University
Chapter 11 Site-Specific Recombination & Transposition of DNA •Molecular Biology Course
There are genetic processes that rearrange DNA sequences and thus lead to a more dynamic genome structure
There are genetic processes that rearrange DNA sequences and thus lead to a more dynamic genome structure
Two classes of genetic recombination Conservative site-specific recombination (CSSR): recombination between two defined sequence elements Transpositional recombination (Transposition): recombination between specific sequences and nonspecific DNA sites
Two classes of genetic recombination • Conservative site-specific recombination (CSSR): recombination between two defined sequence elements • Transpositional recombination (Transposition): recombination between specific sequences and nonspecific DNA sites
Figure 11-1 site-specific recombination sites recombination transposable element transposition 十 Copyright 2004 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 11-1
OUTLINE 1. Conservative Site-Specific Recombination 2. Biological Roles of Site-Specific Recombinatⅰon 3. Transposition 4. Examples of Transposable Elements and Their Regulation 5. VD)J Recombination
OUTLINE 1. Conservative Site-Specific Recombination 2. Biological Roles of Site-Specific Recombination 3. Transposition 4. Examples of Transposable Elements and Their Regulation 5. V(D)J Recombination
Topic 1: Conservative Site- Specific Recombination 1. Exchange of non-homologous sequences at specific DNa sites(what) 2. Mediated by proteins that recognize specific DNA sequences. (how)
Topic 1: Conservative SiteSpecific Recombination 1.Exchange of non-homologous sequences at specific DNA sites(what) 2.Mediated by proteins that recognize specific DNA sequences. (how)