上游克通大￥ Shanghai Jiao Tong Univer Anti-parasitic drugs (抗寄生虫药) 2012.12
Anti-parasitic drugs （抗寄生虫药） 2012.12
上克通大睾 Shanghai Jiao Tong University Anti-malarial drugs (抗疟药)
Shanghai Jiao Tong University Anti-malarial drugs （抗疟药）
Symptoms of 上克通大睾 Malaria Shanghai Jiao Tong University Central- Skin Headache -Chills Plasmodium parasite. Systemic -Sweating Fever Malaria.derived from mala Respiratory Muscular Dry cough aria (bad air)and associated Fatigue -Pain Spleen with s Enlarge- swamp and badly Back- ment -Pain drained areas. Stomach Nausea Spread by mosquito. Vomiting √Anopheles mosquito:the carrier of the causative protozoa Found by Dr.Ronald Ross, Nobel Prize in Medicine in 1902
Shanghai Jiao Tong University Plasmodium parasite. Malaria, derived from mala aria (bad air) and associated with swamp and badly drained areas. Spread by mosquito. Anopheles mosquito: the carrier of the causative protozoa Found by Dr. Ronald Ross, Nobel Prize in Medicine in 1902
上游充通大学 Shanghai Jiao Ton Bite from infected mosquito Life cycle of malaria parasites Infected mosquito Uninfected Primary attack Relapse (due to P.vivax or P.ovale) mosquito Erythrocytic stage of infection Goodman ERYTHROCYTIC Gilman's 12th ed. CYCLE 00 Schizonts Merozoites
Shanghai Jiao Tong University Life cycle of malaria parasites Goodman & Gilman’s 12th ed
上大￥Antimalarial Research stimulated By War Shanghai Jiao Tong University World war I, >15,000 substances synthesized and screened by US, Australia and Great Britain. Vietnam War,increasing problem of resistance to commonly used antimalarials.1968 to 1978,>250,000 compounds investigated by U.S.Army
Shanghai Jiao Tong University World war II, >15,000 substances synthesized and screened by US, Australia and Great Britain. Vietnam War, increasing problem of resistance to commonly used antimalarials. 1968 to 1978, >250,000 compounds investigated by U.S. Army. Antimalarial Research stimulated By War
上游充通大￥ Drug classification Shanghai Jiao Tong University Drugs for controlling symptoms(drugs to suppress erythrocytic phase): artemisinin chloroquine benflumetol Drugs for radical cure of malaria(drugs for the exo- erythrocytic phase(liver)and gametocytes): primaquine Drugs for prophylaxis: pyrimethamine
Shanghai Jiao Tong University Drug classification Drugs for controlling symptoms (drugs to suppress erythrocytic phase): artemisinin chloroquine benflumetol Drugs for radical cure of malaria (drugs for the exoerythrocytic phase (liver) and gametocytes): primaquine Drugs for prophylaxis: pyrimethamine
上克通大睾 Shanghai Jiao Tong University Drugs for controlling symptoms of malaria (控制疟疾症状的药物)
Shanghai Jiao Tong University Drugs for controlling symptoms of malaria （控制疟疾症状的药物）
上游充通大学 Artemisinin(青蒿素) Shanghai Jiao Tong University Isolated from the plant Artemisia annua. HaC iA CH3 Artemisinin
Shanghai Jiao Tong University Artemisinin (青蒿素) Isolated from the plant Artemisia annua
上浒充通大睾 Shanghai Jiao Tong University Artemisinin (青蒿素) The weed Artemisia annua used for many centuries in Chinese herbal medicine as a treatment for fever and malaria. 1971,Chinese chemists isolated from the leafy portions of the plant the substance responsible for its reputed medicinal action. Artemisinin (qinghaosu,arteannuin),determined by X- ray crystallography to be a sesquiterpene e lactone bearing an endoperoxide
Shanghai Jiao Tong University Artemisinin (青蒿素) The weed Artemisia annua used for many centuries in Chinese herbal medicine as a treatment for fever and malaria. 1971, Chinese chemists isolated from the leafy portions of the plant the substance responsible for its reputed medicinal action. Artemisinin (qinghaosu, arteannuin), determined by Xray crystallography to be a sesquiterpene lactone bearing an endoperoxide
上商充通大￥ Shanghai Jiao Tong University 锐人物u题m 药学家屠呦呦 发现青蒿素，获2011拉斯克奖
Shanghai Jiao Tong University