What is the main difference between previously learnt drugs and the "antimicrobial drugs"? "Chemotherapeutic drugs" Narrow definition:any chemical used to treat cancer. Broad definition:
What is the main difference between previously learnt drugs and the “antimicrobial drugs”? “Chemotherapeutic drugs” Narrow definition: any chemical used to treat cancer. Broad definition:
Chemotherapeutic drugs: Anti-microbial drugs Anti-parasitic drugs √Anti-tumor drugs
Chemotherapeutic drugs: Anti-microbial drugs Anti-parasitic drugs Anti-tumor drugs
Data related to infectious diseases Before1940's,pneumonia(肺炎)、 dysentery(痢疾)、typhoid fever(伤寒)、 black death(鼠疫)、diphtheria(白喉)、 malaria(疟疾)、...-incurable disease 1930-1949,Shanghai infectious diseases death:565/100000 persons 1990,0.52/100000 1949,life expectancy 39 years old 2010,82.18(Shanghai))
Before 1940’s, pneumonia(肺炎)、 dysentery(痢疾)、typhoid fever(伤寒)、 black death(鼠疫)、diphtheria(白喉)、 malaria(疟疾)、……- incurable disease 1930-1949, Shanghai infectious diseases death: 565/100000 persons 1990, 0.52/100000 1949, life expectancy 39 years old 2010, 82.18 (Shanghai) Data related to infectious diseases
General principles of antimicrobial therapy ◆Introduction ◆Mechanism of action Antibiotic Resistance General principles of clinical use
General principles of antimicrobial therapy Introduction Mechanism of action Antibiotic Resistance General principles of clinical use
Definition Anti-microbial drugs: Antibiotics:substances produced by or semi-synthesized from various species of microorganisms (bacteria,fungi,and actinomycetes)that suppress the growth of other microorganisms. Synthetic antimicrobial agents,such as sulfonamides(磺胺),quinolones(喹 诺酮),…
Definition Anti-microbial drugs: Antibiotics: substances produced by or semi-synthesized from various species of microorganisms (bacteria, fungi, and actinomycetes) that suppress the growth of other microorganisms. Synthetic antimicrobial agents, such as sulfonamides(磺胺) , quinolones(喹 诺酮) ,
Classification According to the actions against the type of organism 。Antibacterial drugs 。Antiviral drugs ·Antifungal drugs ·Antiprotozoal drugs
Classification According to the actions against the type of organism • Antibacterial drugs • Antiviral drugs • Antifungal drugs • Antiprotozoal drugs
The discovery of Penicillin ● 1928:Alexander Fleming discovered the first antibiotic. He observed that Penicillium fungus made an antibiotic, penicillin,that killed S. aureus. Penicillium Dr Howard W Florey and his colony German associate Dr Ernest Boris Chain attempting to extract the essential substance from Fleming's Bacteria inhibited mould. ● 12 February,1941,the first dose of isolated penicillin was Bacteria injected into a human being Nobel Prize for Medicine in 1945
• 1928: Alexander Fleming discovered the first antibiotic. • He observed that Penicillium fungus made an antibiotic, penicillin, that killed S. aureus. • Dr Howard W Florey and his German associate Dr Ernest Boris Chain attempting to extract the essential substance from Fleming's mould. • 12 February, 1941, the first dose of isolated penicillin was injected into a human being • Nobel Prize for Medicine in 1945 The discovery of Penicillin