Systems Biology Toward System-level Understanding of Biological Systems Hou-Haifeng
Systems Biology ___ Toward System-level Understanding of Biological Systems Hou-Haifeng
What is Systems Theory? By,we mean a bunch of parts that are connected to one another and work together Mathematical Systems Theory is oncerned with the description and understanding of systems by the means of mathematics Analysis Modeling Simulation
What is Systems Theory? ◼ By “system”, we mean a bunch of parts that are connected to one another and work together ◼ Mathematical Systems Theory is oncerned with the description and understanding of systems by the means of mathematics ◼ Analysis Modeling Simulation
Dynamic Systems -Definition A system is an object in which variables of different kinds interact and produce observable signals In a dynamicsystem the current output value depends not only on the current input value but also on its earlier values
Dynamic Systems - Definition ◼ A system is an object in which variables of different kinds interact and produce observable signals ◼ In a dynamic system the current output value depends not only on the current input value but also on its earlier values
Dynamic Systems
Dynamic Systems
What exactly is Systems Biology? Biology went top-down for the last 50 years From cell to protein to gene.. Huge amounts of data produced Challenge:put the pieces back together again Attempts to create predictive models of cells, organs,biochemical processes and complete organisms
What exactly is Systems Biology? ◼ Biology went top-down for the last 50 years ◼ From cell to protein to gene .. ◼ Huge amounts of data produced Challenge: put the pieces back together again ◼ Attempts to create predictive models of cells, organs, biochemical processes and complete organisms
The scope of systems biology is potentially very broad and different sets of techniques may be deployed for each research target.It requires collective efforts from multiple research areas,such as molecular biology,high-precision measurement. MATHEMA computer science,control theory,and other scientific and engineering fields
The scope of systems biology is potentially very broad and different sets of techniques may be deployed for each research target. It requires collective efforts from multiple research areas, such as molecular biology, high-precision measurement, computer science, control theory, and other scientific and engineering fields
What exactly is Systems Biology? a new field in biology that aims at system- level understanding of biological systems to understand biological systems grounded in the molecular level as a consistent framework of knowledge to investigate the behaviour and relationships of all the elements in a particular biological system
What exactly is Systems Biology? ◼ a new field in biology that aims at systemlevel understanding of biological systems ◼ to understand biological systems grounded in the molecular level as a consistent framework of knowledge ◼ to investigate the behaviour and relationships of all the elements in a particular biological system
What exactly is Systems Biology? Healthcare System Biological System Patients DNA RN Insurance Companies
What exactly is Systems Biology?
SYSTEMS BIOLOGY BIOLOGY INFORMATICS Data bases Cton SYSTEMS STUDIES
History Term coined at 1960s,however theoretical people and experimental biologists diverged Renaissance at 1990s Biology becoming cross-disciplinary, information based,high throughput science
History ◼ Term coined at 1960s, however theoretical people and experimental biologists diverged ◼ Renaissance at 1990s ◼ Biology becoming cross-disciplinary, information based, high throughput science