Medical Genetics Chapter 1 Introduction to Medical Genetics by Xiaoying Liu E-mail:1123796489@qq.com Tel:65167282 Office:Room 518,Basic Medicine Building Biology Department,School of Life Science This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more informatior
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Medical Genetics Outline ◆Introduction; What is Medical Genetics? ◆Human Genomics; ◆Genetic disorders; Tasks of Medical Genetics in Medical Education. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
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Medical Genetics 1.Introduction Gregor Mendel(1822-1884) was the founder of modern genetics Mendel first discovered the principles of heredity by crossing different varieties of pea plants and analyzing the pattern of transmission of traits in subsequent generations. The first law(or law of segregation)of Mendel; The second law(or law of independent assortment)of Mendel. https://en.wikipedia.org/wiki/Gregor Mendel 3 This document is produced by trial version of Print2Flash.Visit www.printflash.com for more information
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Medical Genetics 盟里出 This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
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Medical Genetics Punnett Square (the relation between genotype and phenotype) pollen B b B BB Bb pistil yy ♀ b Bb bb This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
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Medical Genetics The Punnett square is a diagram that is used to predict an outcome of a particular cross or breeding experiment. The Punnett square is a tabular summary of every possible combination of one maternal allele with one paternal allele for each gene being studied in the cross. These tables give the correct probabilities for the genotype outcomes of independent crosses where the probability of inheriting copies of each parental allele is independent. The Punnett Square is a visual representation of Mendelian inheritance. https://en.wikipedia.org/wiki/Punnett square 6 This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more informatior
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Medical Genetics Phenotypes and Genotypes Mother Father Dr Dr DD Dr rr This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
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Medical Genetics “All medicine is genetics” ---Mckusick V.A. (Father of Medical Genetics https://en.wikipedia.org/wiki/V ictor_A._McKusick Victor A.McKusick,MD @tahr21,1921-cap222008 “Medicine in future is molecular genetics” ---Dulbecco R 8 This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
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Medical Genetics Chromosome theory of inheritance -Morgan B B B -C -c Figure 1.3 Thomas Hunt Morgan Nobel Prize in Physiology or Medicine in 1933. Model organism:Drosophila melanogaster. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
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Medical Genetics Characteristics of Drosophila melanogaster This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information
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