上降文通大学 SHANGHAI JLAO TONG UNIVERSITY 临床医学与材料 孙康教授 漏 材料科学与工程学院 Wn ksun@sjtu.edu.cn 2018-10-06 泰 SHANG 1日gG
临床医学与材料 （一） 孙康 教授 材料科学与工程学院 ksun@sjtu.edu.cn 2018-10-06
中国未来空间站 上游充通大学 菌介 SHANGHAI JIAO TONG UNIVERSITY 人2想 A350 XWB STRUCTURAL DESIGN Nose section (carbonfibre or aluminium) Fin (carbonfibre) 13m 18m -16m 法生书名装非车带卡书车车车车华装 位人航吴 有八 Rear fuselage Fuselage section(carbonfibre skin panels. (carbonfibre,one doublers,joints and stringers,with aluminium frames) piece section) Four shell skin A350 XWB material breakdown panel concept 7% 20% Aluminium/Aluminium lithium ●Steel 1% 52% Titanium Composite ●Miscellaneous Aluminium frames FLIGHT Carbonfibre skin panel Note:AS50-900 shown 天官舱内 APPAMO日US
上游充通大学 silkworm silks SHANGHAI JIAO TONG UNIVERSITY
silkworm silks
上游充通大粤 SHANGHAI JIAO TONG UNIVERSITY 1.0 Black:4mm/s 0.9- Red:13mm/s Green:20mm/s 0.8- Blue:27mm/s 0.7- 0.6- 0 0.3 0.2 0.1 0.0 0.00 0.05 0.10 0.150.20 0.25 0.30 0.35 0.40 Strain
0.00 0.05 0.10 0.15 0.20 0.25 0.30 0.35 0.40 0.0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1.0 Stress(GPa) Strain Black:4mm/s Red:13mm/s Green:20mm/s Blue:27mm/s
上游充通大学 SHANGHAI JIAO TONG UNIVERSITY (a) Fibril Stratified structure Fibril is aggregate made Fibroin is bundle made of sericin from many microfibrils from many fibrils Aperture of Fibroin microfibril Cocoon_fiber Crystal region、. Molecular conformation of fibroin in crystal region (b) Amorphous region- (c) 蚕丝素蛋白纤维 Crystal 的不规则性 -region Amorphous region (d) Bio-macromolecules
蚕丝素蛋白纤维 的不规则性
上游充通大学 如料华 SHANGHAI JIAO TONG UNIVERSITY 溶解签 料系 给料系 仿机 拉帅浴 水洗 88 干燥器 供牵神机 处理机 修醛帝 水洗蹈 M中 干燥箱 聚乙冲醇短所推生产戏程图 纺慈机税， 打包 membrane sericin lll sericin ll sencm fibroin posterior"Imiddle part anterior part part posterior middle division anterior spinneret cocoon division divison filament
上游充通大学 SHANGHAI JIAO TONG UNIVERSITY States of liquid silk fibroin in B.mori.silk gland S泳 Postericr Middle Division Antericr Gland Division Division Pcsterior Middle Anterior Concentration) 12 25 26 26 30 Conformation Random-coil Random-col B-form pH 6.9 5.6 5.2 5.0 4.8 Viscosity Middle High High High Low State Gel Gel Gel Gel-sol K+(103%) 一- 30.2 29.5 33.3 Ca2+(103%) 17.7 460 507 Water Content 88 75 74 74 70 Freezing Water( 813 63.2 57.2 56.9 Non-freezing Water (% 6.9 118 16.8 17.1 -
States of liquid silk fibroin in B. mori. silk gland
上游充通大学 SHANGHAI JIAO TONG UNIVERSITY 固体丝，高取向的邹-折叠结构 拉伸应力 水分挥发 30%水凝胶，阝-折叠，向列型液晶 高剪切应力 25%水凝胶，α-螺旋+拉开的螺旋，液晶形成 分子链进一步有序排列 23%水凝胶，无规的螺旋+-螺旋 分子链排列 20%水凝胶，复合螺旋 Silkgland of Bombyx mori. A~B:Ant.divi.,~35mm,0.05~0.3mmo; 蛋白质浓度增大 有序化开始 B~C:Middle divi.,~65mm,1.2~2.5mmo; C~D:Post.divi.,~220,0.4~0.8mm 12%丝素水溶液，无规线团
Silkgland of Bombyx mori. A~B: Ant. divi., ~ 35mm, 0.05~0.3mm; B~C: Middle divi., ~65mm, 1.2~2.5mm; C~D: Post. divi., ~220, 0.4~0.8mm 拉伸应力 水分挥发 高剪切应力 蛋白质浓度增大 有序化开始 分子链排列 分子链进一步有序排列 12％丝素水溶液，无规线团 20％水凝胶，复合螺旋 23％水凝胶，无规的螺旋+-螺旋 25％水凝胶，-螺旋+拉开的螺旋，液晶形成 30％水凝胶，-折叠，向列型液晶 固体丝，高取向的-折叠结构
上游充通大学 SHANGHAI JIAO TONG UNIVERSITY Better life...... HEALTH IN 17 1m THE SDG ERA 16怒 袖 2 MOBILIOING PARINERS 0 ewr NEEDS OF THE POOR 15 AND ACCOUNT FOR AND CONSEQUENCES 4 OFALL FORMS OF SDG RESPONSES Li EDUCATION FOR 14m 3 GOOD HEALTH AND WELL-BEING 5 STOCKS TO IMPROVE SAFE ANO DIVERS FIED VICLENCE AGAINST HEALTHY DIETS WOMEN 13 PROTECNHEUH FROM CLIMATE RISKS 6常 At镇AND SANITATION POR AEL ENSURE HEALTHY LIVES AND PROMOTE WELL-BEING FOR ALL AT ALL AGES HOMES AND LIVES 12 NO SAFE ANO MORE ENSURING EQUITABLE ACCESS TO GROWTH ACTIVE LNVING 11器 AFFORDAELE ESSENTIA ON STRONGE段 MEDICAL FRODUCTS 8 PRIMAITY CARE 10s 9品 World Health Organization WWW.WHO.INT/SDGS @B骺GALS
Better life……
上游充通大学 微创手术 SHANGHAI JIAO TONG UNIVERSITY 图 图二 图三m
微创手术