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《生物技术安全》(英文版) Chapter 7. Guidelines for laboratory and facility commissioning试运转

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Laboratory/facility commissioning may be defined as the systematic review and documentation process signifying that specified laboratory structural components, systems and/or system components have been installed, inspected, functionally tested and verified to meet national or international standards, as appropriate.
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Chapter 7. Guidelines for laboratory and facility commissioning试运转

Chapter 7. Guidelines for laboratory and facility commissioning试运转

U Laboratory/facility commissioning may be defined as the systematic review and documentation process signifying that specified laboratory structural components, systems and/or system components have been installed, inspected, functionally tested and verified to meet national or international standards, as appropriate

❑Laboratory/facility commissioning may be defined as the systematic review and documentation process signifying that specified laboratory structural components, systems and/or system components have been installed, inspected, functionally tested and verified to meet national or international standards, as appropriate

UThe respective building systems design criteria and design function esta blish these requirements In other words, laboratories designated as Biosafety levels 1-4 will have different and increasingly complex commissioning requirements Geographical and climatic conditions, such as geological fault lines地质断层带 or extreme heat,cold or humidity may also affect the laboratory design and therefore the commissioning requirements

❑The respective building system’s design criteria and design function establish these requirements. In other words, laboratories designated as Biosafety Levels 1–4 will have different and increasingly complex commissioning requirements. Geographical and climatic conditions, such as geological fault lines地质断层带 or extreme heat, cold or humidity may also affect the laboratory design and therefore the commissioning requirements

aUpon the completion of the commissioning process; the pertinent有关的 structural components and support systems will have been subjected to the various operating conditions and failure modes that can be reasonably expected, and will have been approved. u The commissioning process and acceptance criteria should be established early, preferably during the programming phase of the construction or renovation project

❑Upon the completion of the commissioning process, the pertinent有关的 structural components and support systems will have been subjected to the various operating conditions and failure modes that can be reasonably expected, and will have been approved. ❑The commissioning process and acceptance criteria should be established early, preferably during the programming phase of the construction or renovation project

a By acknowledging the commissioning process early in the project, architects, engineers, safety and health personnel and ultimately the laboratory occupants understand the performance requirements of the specific la boratory and set uniform expectations for laboratory and/or facility performance

❑By acknowledging the commissioning process early in the project, architects, engineers, safety and health personnel and ultimately the laboratory occupants understand the performance requirements of the specific laboratory and set uniform expectations for laboratory and/or facility performance

UThe commissioning process provides the institution and the surrounding community with a greater degree of confidence that the structural electrical, mechanical and plumbing itf systems containment and decontamination systems, and security and alarm systems will operate as designed, to assure containment of any potentially dangerous microorganisms being worked with in a particular laboratory or animal facility

❑The commissioning process provides the institution and the surrounding community with a greater degree of confidence that the structural, electrical, mechanical and plumbing管道 systems, containment and decontamination systems, and security and alarm systems will operate as designed, to assure containment of any potentially dangerous microorganisms being worked with in a particular laboratory or animal facility

a Commissioning activities generally begin during the programming phase of the project and proceed through the construction and subsequent warranty period for the laboratory/facility. Warranty periods should generally extend for one year following occupancy

❑Commissioning activities generally begin during the programming phase of the project and proceed through the construction and subsequent warranty period for the laboratory/facility. Warranty periods should generally extend for one year following occupancy

uIt is recommended that a commissioning agent is retained who is independent of the architectural, engineering and construction firms involved in the design and construction

❑It is recommended that a commissioning agent is retained who is independent of the architectural, engineering and construction firms involved in the design and construction

UThe commissioning agent serves as an advocate for the institution constructing or renovating the la boratory and should be considered as a member of the design team; involvement of the agent in the early programming phase of the project is essential. uIn some cases the institution may act as its own commissioning agent. In the case of more complex laboratory facilities biosafety levels 3 or 4), the institution may wish to retain an outside commissioning agent who has demonstrated experience and success in the commissioning of complex biosafety laboratory and animal facilities

❑The commissioning agent serves as an advocate for the institution constructing or renovating the laboratory and should be considered as a member of the design team; involvement of the agent in the early programming phase of the project is essential. ❑In some cases, the institution may act as its own commissioning agent. In the case of more complex laboratory facilities (Biosafety Levels 3 or 4), the institution may wish to retain an outside commissioning agent who has demonstrated experience and success in the commissioning of complex biosafety laboratory and animal facilities

aWhen an independent commissioning agent is used. the institution should still be a member of the commissioning team. It is recommended that, in addition to the commissioning agent, the institutions Safety Officer, Project Officer, Programme Manager and a representative of the Operations and Maintenance staff are also part of the team

❑When an independent commissioning agent is used, the institution should still be a member of the commissioning team. It is recommended that, in addition to the commissioning agent, the institution’s Safety Officer, Project Officer, Programme Manager and a representative of the Operations and Maintenance staff are also part of the team

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