肠易激综合征的新概念 Newest concepts in irritable bowel syndrome IBS 张虎 华西医院消化科
肠易激综合征的新概念 Newest concepts in irritable bowel syndrome IBS 张虎 华西医院消化科
新概念:一种以腹痛或腹部不适伴排便 习惯改变为特征的功能性肠病 a group of functional bowel disorders in which discomfort or pain is associated with defecation or a change in bowel habit, and with features of disordered defecation
新概念:一种以腹痛或腹部不适伴排便 习惯改变为特征的功能性肠病 …a group of functional bowel disorders in which discomfort or pain is associated with defecation or a change in bowel habit , and with features of disordered defecation
Bs-Psychosocial lBS Non-patients normal Psychologic disturbance relates to patients who see physicians Psycho Psychosocial factors influence logic lBs patients health care seeking disturb ance
•Psychologic disturbance relates to patients who see physicians • Psychosocial factors influence health care seeking IBS Non-patients normal IBS patients Psycho logic disturb ance IBS - Psychosocial
流行病学研究 西方国家患病率5-24% 美 人群10-20% 就诊率30%$80亿 国内 北京潘国宗 7.26 广州陈旻湖》56 就诊率22.4%
流行病学研究 西方国家 患病率 5---24% 美国 人群 10-20% 就诊率 30% $80亿 国内 北京 潘国宗 7.26% 广州 陈旻湖 5.6% 就诊率 22.4%
Development of IBS pathophysiology Abnormalnetwork regulation IBS molecular biology Of nerve-immune-endocrine inflammation 5-HT mediated hypersensitivity and gut motility Brain-gut interaction Visceral hypersensitivity Abnormal motor function 195019601970198019902000
Development of IBS pathophysiology { inflammation 5-HT mediated hypersensitivity and gut motility Brain-gut interaction Visceral hypersensitivity Abnormal motor function 1950 1960 1970 1980 1990 2000 Abnormal network regulation Of nerve-immune-endocrine IBS molecular biology ……