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复旦大学附属妇产科医院:《妇产科学》课程教学资源(PPT课件讲稿)preeclampsia

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Preeclampsia-Eclampsia Definition Toxemia Gestosis Preeclampsia-Eclampsia EPH Syndrome
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Preeclampsia-Eclampsia Prof. duan Tao M D Shanghai 1st Maternity and Infant Hospital o ⊙ Ceded

Preeclampsia-Eclampsia Prof. Duan Tao,M.D. Shanghai 1st Maternity and Infant Hospital

Preeclampsia-Eclampsia Definition 4 Toxemia t Gestosis t Preeclampsia- Eclampsia +Pregnancy Induced Hyperten YO EPH Syndrome ⊙ Ceded

Preeclampsia-Eclampsia Definition: Toxemia Gestosis Preeclampsia-Eclampsia Pregnancy Induced Hypertension EPH Syndrome

人 Theories about causes Still Unknown +Utero-placental ischemia 9+ Neuro-endocrino \ogr: PGr,/TXA +Immunology-hereditary Chronic DIc ⊙ Ceded

Theories about causes Still Unknown: Utero-placental ischemia: Neuro-endocrinology:PGI2/TXA2 Immunology-hereditary: Chronic DIC:

Theory +Primipaternity Robillard py. Eur j Obstet Gynecol Reprod Biol, 1999 8+Dekker: 392 multiparous PIH women 22-25% have new partners, 3. 4% in control group ⊙ Ceded

Theory Primipaternity: Robillard PY. Eur J Obstet Gynecol Reprod Biol, 1999. Dekker: 392 multiparous PIH women , 22-25% have new partners, 3.4% in control group

My Theory +Trigger off theory The open Shield in Chicago Lying -In Hospital ⊙ Ceded

My Theory Trigger off theory : The open Shield in Chicago Lying –In Hospital

Diagnosis Chinese way Mild preeclampsia BP:>140790mmHg but <150/100mmHg or with an elevation of 30/15 mmHg Edema: and/or Proteinuria: Trace ⊙ Ceded

Diagnosis Chinese way: Mild preeclampsia BP :  140/90mmHg, but <150/100mmHg, or with an elevation of 30/15 mmHg Edema: and/or Proteinuria: Trace

Diagnosis Moderate preeclampsia BP:> 150/100mmHg, but <160/110mmHg Edema: and/or Proteinuria: 1+ ⊙ Ceded

Diagnosis Moderate preeclampsia BP :  150/100mmHg, but <160/110mmHg, Edema: and/or Proteinuria: 1+

Diagnosis Severe preeclampsia BP:≥160/110mmH Edema: and/or Proteinuria: 2+/4+ ⊙ Ceded

Diagnosis Severe preeclampsia BP :  160/110mmHg Edema: and/or Proteinuria: 2+~4+

Pathophysiolo gy t Vasospasm " haemorrage& necrosis" end organ changes +Reduced placental perfusion- IUGR foetal death + Increased cardiac output +Increased extra cellular fluid ofme Ceded

Pathophysiology Vasospasm “haemorrage & necrosis” end organ changes Reduced placental perfusion→ IUGR & foetal death Increased cardiac output Increased extra cellular fluid volume

Pathophysiolo gy t Haemoconcentration + Hypercoagulability-DIC-reduced clotting factors -bleeding t Reduced gfr oliguria- anuria +No electrolytic imbalance ro(O ⊙ Ceded

Pathophysiology Haemoconcentration Hypercoagulability-DIC - reduced clotting factors - bleeding Reduced GFR oligouria - anuria No electrolytic imbalance

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