Preeclampsia-Eclampsia Prof. duan Tao M D Shanghai 1st Maternity and Infant Hospital o ⊙ Ceded
Preeclampsia-Eclampsia Prof. Duan Tao,M.D. Shanghai 1st Maternity and Infant Hospital
Preeclampsia-Eclampsia Definition 4 Toxemia t Gestosis t Preeclampsia- Eclampsia +Pregnancy Induced Hyperten YO EPH Syndrome ⊙ Ceded
Preeclampsia-Eclampsia Definition： Toxemia Gestosis Preeclampsia-Eclampsia Pregnancy Induced Hypertension EPH Syndrome
人 Theories about causes Still Unknown +Utero-placental ischemia 9+ Neuro-endocrino \ogr: PGr,/TXA +Immunology-hereditary Chronic DIc ⊙ Ceded
Theories about causes Still Unknown: Utero-placental ischemia: Neuro-endocrinology：PGI2/TXA2 Immunology-hereditary： Chronic DIC：
Theory +Primipaternity Robillard py. Eur j Obstet Gynecol Reprod Biol, 1999 8+Dekker: 392 multiparous PIH women 22-25% have new partners, 3. 4% in control group ⊙ Ceded
Theory Primipaternity: Robillard PY. Eur J Obstet Gynecol Reprod Biol, 1999. Dekker: 392 multiparous PIH women , 22-25% have new partners, 3.4% in control group
My Theory +Trigger off theory The open Shield in Chicago Lying -In Hospital ⊙ Ceded
My Theory Trigger off theory ： The open Shield in Chicago Lying –In Hospital
Diagnosis Chinese way Mild preeclampsia BP:>140790mmHg but <150/100mmHg or with an elevation of 30/15 mmHg Edema: and/or Proteinuria: Trace ⊙ Ceded
Diagnosis Chinese way: Mild preeclampsia BP : 140/90mmHg, but <150/100mmHg, or with an elevation of 30/15 mmHg Edema: and/or Proteinuria: Trace
Diagnosis Moderate preeclampsia BP:> 150/100mmHg, but <160/110mmHg Edema: and/or Proteinuria: 1+ ⊙ Ceded
Diagnosis Moderate preeclampsia BP : 150/100mmHg, but <160/110mmHg, Edema: and/or Proteinuria: 1+
Diagnosis Severe preeclampsia BP:≥160/110mmH Edema: and/or Proteinuria: 2+/4+ ⊙ Ceded
Diagnosis Severe preeclampsia BP : 160/110mmHg Edema: and/or Proteinuria: 2+~4+
Pathophysiolo gy t Vasospasm " haemorrage& necrosis" end organ changes +Reduced placental perfusion- IUGR foetal death + Increased cardiac output +Increased extra cellular fluid ofme Ceded
Pathophysiology Vasospasm “haemorrage & necrosis” end organ changes Reduced placental perfusion→ IUGR & foetal death Increased cardiac output Increased extra cellular fluid volume
Pathophysiolo gy t Haemoconcentration + Hypercoagulability-DIC-reduced clotting factors -bleeding t Reduced gfr oliguria- anuria +No electrolytic imbalance ro(O ⊙ Ceded
Pathophysiology Haemoconcentration Hypercoagulability-DIC - reduced clotting factors - bleeding Reduced GFR oligouria - anuria No electrolytic imbalance