Chaper 13 Respiratory failure Zhao Mingyao BMC.ZZU
Chaper 13 Zhao Mingyao BMC.ZZU
Respiration= ventilation t gas exchange Ventilation: alveoli enlarging to set up p gradient airway fluency to let gas flow gas exchange: area distance efficiency(v/Q) physiology view
Respiration = ventilation + gas exchange Ventilation: alveoli enlarging to set up P gradient airway fluency to let gas flow gas exchange: area distance efficiency (V/Q) ------ physiology view
Air Out nasal cavity aryan larynx trachea epiglottis bronchus right lung 人.了 diaphragm left lung neural
1. Concept of Repiratory Failure Respiratory system fails to adequately oxygenate the blood with/without retention of CO2, it is generally defined as a pao 60mmHg. with /without Paco2 >50mmHg
1.Concept of Repiratory Failure Respiratory system fails to adequately oxygenate the blood with/without retention of CO2 , it is generally defined as a PaO2 50mmHg
2. Classification of According to (duration Acute: minutes to days Chronic: over months to years (2)primary site Central: head injury, encephalitis Peripheral: asthma, pneumonia, emphysema
2.Classification of ~ (1)duration Acute : minutes to days Chronic: over months to years (2)primary site Central : head injury, encephalitis Peripheral: asthma, pneumonia, emphysema According to
B3)blood-gas Type I:PaO2↓ Type I:PaO2↓+PaCO2 (4 ) pathogenesis ventilation blood gas exchange: diffusion v/Q anatomy shunt
(3)blood-gas Type I : PaO2 Type II: PaO2 + PaCO2 (4)pathogenesis ventilation blood gas exchange: diffusion V/Q anatomy shunt
Section 1 Etiology and pathogenesis Respiration ventilation gas exchange
Section 1 Etiology and pathogenesis Respiration = ventilation + gas exchange
Mechanism of re 1. Hypoventilation (Restrictive Extralung intralung Central airway (2 )obstructive Pe eripheral airway
1. Hypoventilation Mechanism of RF (1)restrictive ~ (2)obstructive ~ Central airway ~ Peripheral airway ~ Extralung intralung
Ventilation(does work dynamic force overcomes resistant force (elastic nonelastic m) ----physics view
Ventilation (does work) = dynamic force overcomes resistant force (elastic ~ + nonelastic ~) ----physics view
(1) Restrictive MEDULLA CAROTID BODY Major causes: Ⅸ NERVE SPINAL CORD CNS and nerves 6 THORACIC CAGE MUSCLE Respiratory muscles chest wall AIRWAYS and pleura Lung( Alveoli) distension I Alveoli distensibility t
(1) Restrictive ~ Alveoli distensibility Major Causes: CNS and nerves Respiratory muscles, chest wall and pleura Lung( Alveoli) distension
