重慶醫科大学ChongqingMedical University《生物化学D》（供六年制临床医学专业来华留学生使用）教学大纲基础医学院生物化学与分子生物学教研室编写2021年3月
《生物化学 D》 （供六年制临床医学专业来华留学生使用） 教 学 大 纲 基础医学院生物化学与分子生物学教研室编写 2021 年 3 月
前言一、基本信息（宋体小四粗体，1.5倍行间距）课程名称：生物化学学时学分：4.5学分、72学时（包含72理论学时）适用专业：临床医学留学生本科先修课程：二、课程简介生物化学与分子生物学是一门在分子水平上研究生命现象的科学，其核心在于从分子水平上阐明生命活动的本质和规律。生物化学与分子生物学是生物医学领域的重要基础学科和前沿领头学科，也是医学教育中重要的基础主干课程。其主要内容包括生物大分子的结构与功能、生物体内各种物质的代谢及其调节等。三、课程目标1.思想道德与职业素质目标（含课程思政目标）培养在华留学生的“科学无国界”大局观和“知华友华爱华”情怀，培养在华留学生自主学习、团队合作、解决问题、创新思维等综合素质。2.知识目标①掌握理解生物大分子核酸与蛋白质结构特点与功能，以及结构与功能的关系；②掌握糖类、脂质和氨基酸的主要代谢途径：③掌握物质代谢的基本规律，以及物质代谢与能量代谢的关系；④掌握生物化学专业词汇，为英文专业文献阅读做准备。3.技能目标紧密结合临床医学专业岗位胜任力的培养导向，引导和培养学生能够利用所学的生物化学知识解答分析各类复杂疾病（比如代谢性疾病）的分子发病机制，四、教学要求本大纲主要依据最新的临床执业医师考试大纲，并结合硕士研究生入学考试即联考西医综合考试大纲，以及学校的教学计划和学时安排而制订，主要供临床医学等医学类各专业教学使用。教学内容不仅全面涵盖了各种国家统一性考试对医学生本学科知识的要求，而且也兼顾了日后学生的实际需要和学科的最新发展动态和进展。注意培养学生的自学能力、口头表达能力、文学表达能力、观察能力、批判性思维等，以
前 言 一、基本信息（宋体小四粗体，1.5 倍行间距） 课程名称：生物化学 学时学分：4.5 学分、72 学时（包含 72 理论学时） 适用专业：临床医学留学生本科 先修课程： 二、课程简介 生物化学与分子生物学是一门在分子水平上研究生命现象的科学，其核心在于从 分子水平上阐明生命活动的本质和规律。生物化学与分子生物学是生物医学领域的重 要基础学科和前沿领头学科，也是医学教育中重要的基础主干课程。其主要内容包括 生物大分子的结构与功能、生物体内各种物质的代谢及其调节等。 三、课程目标 1.思想道德与职业素质目标（含课程思政目标） 培养在华留学生的“科学无国界”大局观和“知华友华爱华”情怀，培养在华留 学生自主学习、团队合作、解决问题、创新思维等综合素质。 2.知识目标 ①掌握理解生物大分子核酸与蛋白质结构特点与功能，以及结构与功能的关系； ②掌握糖类、脂质和氨基酸的主要代谢途径； ③掌握物质代谢的基本规律，以及物质代谢与能量代谢的关系； ④掌握生物化学专业词汇，为英文专业文献阅读做准备。 3.技能目标 紧密结合临床医学专业岗位胜任力的培养导向，引导和培养学生能够利用所学的 生物化学知识解答分析各类复杂疾病（比如代谢性疾病）的分子发病机制。 四、教学要求 本大纲主要依据最新的临床执业医师考试大纲，并结合硕士研究生入学考试即联 考西医综合考试大纲，以及学校的教学计划和学时安排而制订，主要供临床医学等医 学类各专业教学使用。教学内容不仅全面涵盖了各种国家统一性考试对医学生本学科 知识的要求，而且也兼顾了日后学生的实际需要和学科的最新发展动态和进展。注意 培养学生的自学能力、口头表达能力、文字表达能力、观察能力、批判性思维等，以
全面提高学生的综合素质。五、教学方法教师必须认真地研究教材，按照本大纲的要求进行教学。教师应掌握好课堂教学的难点和重点，在做好基本知识讲授的同时，与临床方面作一些必要的联系，并适当反映学科的新进展、新动向。在日常教学过程中，采用线上线下混合式教学模式（疫情期间采用线上教学模式），综合运用案例教学、主题沙龙小组讨、翻转课堂等教学方法和教学手段，重点引导和培养学生综合运用已学习掌握的基本理论，解决复杂问题的综合能力和复杂思维。六、考核方式本课程采用形成性评价，具体的形成性评价方案如下：项目权重评价指「考察能力评分标准标课前在综合评定学生在线学习活跃度，取下述1-2部线预习分成绩的平均分：微课视自主学习、自学1.在线时长：至少30分钟/周，≥10小时为1频和课能力、协作学00分（10分/1小时）在线10%件；答习、自律性、分2.课程论坛：在答疑讨论区或各视频下方自主学习疑讨论析解决问题能力讨论区，发帖或回复"数量：≥10次，100等区提问分。<10次，10分/1次。形成性评价和回答3.辅助指标：进入课程次数，学习播课视频次(30% )问题等数：≥20次，100分。<20次，5分/1次。在线网络教学在线平台实施和自在线提自主学习、自学提交交课程能力、分析解决动统计10%百分制，取平均分。课程作业问题能力等作业知识点识记、平时理论知识掌握运各章内容都将在学习后的下一周安排在线测10%掌握和测试用能力试。百分制，取平均分。运用情况知识点总结性评价识记、期末理论知识掌握运70%(70% )掌握和期末考易系统网考，一张试卷，百分制考试用能力考易网考运用情况
全面提高学生的综合素质。 五、教学方法 教师必须认真地研究教材，按照本大纲的要求进行教学。教师应掌握好课堂教学 的难点和重点，在做好基本知识讲授的同时，与临床方面作一些必要的联系，并适当 反映学科的新进展、新动向。在日常教学过程中，采用线上线下混合式教学模式（疫 情期间采用线上教学模式），综合运用案例教学、主题沙龙小组讨、翻转课堂等教学方 法和教学手段，重点引导和培养学生综合运用已学习掌握的基本理论，解决复杂问题 的综合能力和复杂思维。 六、考核方式 本课程采用形成性评价，具体的形成性评价方案如下： 项目 权重 评价指 标 考察能力 评分标准 形成性评价 （30%） 在线网络教学 平台实施和自 动统计 在线 学习 10% 课前在 线预习 微课视 频和课 件；答 疑讨论 区提问 和回答 问题等 自主学习、自学 能力、协作学 习、自律性、分 析解决问题能力 等 综合评定学生在线学习活跃度，取下述 1-2 部 分成绩的平均分： 1. 在线时长：至少 30 分钟/周，≥10 小时为 1 00 分（10 分/1 小时） 2. 课程论坛：在答疑讨论区或各视频下方自主 讨论区，"发帖或回复"数量：≥10 次，100 分。<10 次，10 分/1 次。 3. 辅助指标：进入课程次数，学习播课视频次 数：≥20 次，100 分。<20 次，5 分/1 次。 在线 提交 课程 作业 10% 在线提 交课程 作业 自主学习、自学 能力、分析解决 问题能力等 百分制，取平均分。 平时 测试 10% 知识点 识记、 掌握和 运用情 况 理论知识掌握运 用能力 各章内容都将在学习后的下一周安排在线测 试。百分制，取平均分。 总结性评价 （70%） 考易网考 期末 考试 70% 知识点 识记、 掌握和 运用情 况 理论知识掌握运 用能力 期末考易系统网考，一张试卷，百分制
教材、教辅用书与参考书目根据在华留学生教学情况，并结合中国执业医师考试大纲，教研室选定了相关的教材和参考数目，并已更新到最新版本。另外，教研室还自编教辅用书，更好地帮助在华留学生加强巩固重点和难点。一、教材1.Emine ErcikanAbali,SusanD.Cline,DavidS.Franklin,SusanMViselliLippincott's Illustrated Reviews:Biochemistry,8thEdition.AlphenaandenRijn:WoltersKluwer.2022二、教辅用书1.BiochemistryLearningGuidelines&ReviewTests.生物化学与分子生物学教研室自编。三、参考书目1. David L. Nelson, Michael M. Cox. Lehninger Principles of Biochemistry. 8th EditionNewYork: W.H.Freeman and Company.2021.2.Victor W.Rodwell, David A. Bender, Kathleen M.Botham, Peter J.Kennelly, PAnthony Weil.Harper's illustrated biochemistry.31th Edition.NewYork:McGraw-HillEduation. 2018
教材、教辅用书与参考书目 根据在华留学生教学情况，并结合中国执业医师考试大纲，教研室选定了相关的 教材和参考数目，并已更新到最新版本。另外，教研室还自编教辅用书，更好地帮助 在华留学生加强巩固重点和难点。 一、教材 1. Emine Ercikan Abali, Susan D. Cline, David S. Franklin, Susan M. Viselli. Lippincott's Illustrated Reviews: Biochemistry, 8th Edition. Alphen aan den Rijn: Wolters Kluwer. 2022. 二、教辅用书 1. Biochemistry Learning Guidelines & Review Tests. 生物化学与分子生物学教研室 自编。 三、参考书目 1. David L. Nelson, Michael M. Cox. Lehninger Principles of Biochemistry. 8th Edition. New York: W. H. Freeman and Company. 2021. 2. Victor W. Rodwell, David A. Bender, Kathleen M. Botham, Peter J. Kennelly, P. Anthony Weil. Harper's illustrated biochemistry. 31th Edition. New York: McGraw-Hill Eduation. 2018
目录Appendix: Clinical Case study9UNITI Protein Structure and Function2Chapter 1 Amino Acids.2Chapter2Structureof ProteinsChapter3GlobularProteins3Chapter4EnzymesChapter5VitaminsDUNIT I Bioenergetics and Carbohydrate MetabolismXChapter 6BioenergeticsChapter7Introduction tocarbohydrates.Chapter8IntroductiontometabolismandglycolysisChapter 9 Tricarboxylic acid cycle, pyruvate dehydrogenase complex and oxidativephosphorylationChapter 10 Gluconeogenesis.6Chapter 11 Glycogen metabolism.7Chapter12Metabolismofmonosaccharides and disaccharidesChapter13 Pentose phosphate pathway and nicotinamide adenine dinucleotide phosphate.d.8Chapter 14 Glycosaminoglycans, proteoglycans, and glycoproteinsUNIT II Lipid Metabolism..9Chapter 15Dietary Lipid Metabolism.9Chapter 16Fatty Acid,Ketone Body,and Triacylglycerol Metabolism9..10Chapter 17 Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism.....10Chapter 18 Cholesterol, Lipoprotein, and Steroid MetabolismUNITIVNitrogen Metabolism1111Chapter 19 Amino Acids: Disposal of Nitrogen.12Chapter20AminoAcidsDegradationandSynthesisChapter 21 Conversion of amino acids to specialized products12
目 录 Appendix: Clinical Case study .2 UNIT I Protein Structure and Function.2 Chapter 1 Amino Acids.2 Chapter 2 Structure of Proteins .2 Chapter 3 Globular Proteins.3 Chapter 4 Enzymes.3 Chapter 5 Vitamins.4 UNIT II Bioenergetics and Carbohydrate Metabolism .4 Chapter 6 Bioenergetics .4 Chapter 7 Introduction to carbohydrates.5 Chapter 8 Introduction to metabolism and glycolysis.5 Chapter 9 Tricarboxylic acid cycle, pyruvate dehydrogenase complex and oxidative phosphorylation .6 Chapter 10 Gluconeogenesis.6 Chapter 11 Glycogen metabolism .7 Chapter 12 Metabolism of monosaccharides and disaccharides.7 Chapter 13 Pentose phosphate pathway and nicotinamide adenine dinucleotide phosphate .8 Chapter 14 Glycosaminoglycans, proteoglycans, and glycoproteins.8 UNIT III Lipid Metabolism.9 Chapter 15 Dietary Lipid Metabolism.9 Chapter 16 Fatty Acid, Ketone Body, and Triacylglycerol Metabolism.9 Chapter 17 Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism.10 Chapter 18 Cholesterol, Lipoprotein, and Steroid Metabolism.10 UNIT IV Nitrogen Metabolism.11 Chapter 19 Amino Acids: Disposal of Nitrogen .11 Chapter 20 Amino Acids Degradation and Synthesis.12 Chapter 21 Conversion of amino acids to specialized products.12
Chapter22Nucleotidemetabolism.13UNIT V Integration of Metabolism...14Chapter 23 Metabolic effects of insulin and glucagon.....14Chapter 24Thefeed-fast cycle...14...15Chapter25Diabetes mellitus.Chapter26Nutrition....16
Chapter 22 Nucleotide metabolism .13 UNIT V Integration of Metabolism.14 Chapter 23 Metabolic effects of insulin and glucagon.14 Chapter 24 The feed-fast cycle.14 Chapter 25 Diabetes mellitus.15 Chapter 26 Nutrition.16
教学时数分配表72学时）(共 自学实验示教备注教学内容理论1000IntroductionUNIT I: Protein Structure and Function0001Chapter 1 : Amino Acids3000Chapter 2: Structure of Proteins3000Chapter 3: Globular Proteins4000Chapter 4:Enzymes2000Chapter 5: VitaminsUNIT II:Bioenergetics and Carbohydrate Metabolism3000Chapter 6: Bioenergetics1000Chapter 7: Introduction to Carbohydrates0300Chapter 8: Introduction to Metabolism and Glycolysis000Chapter 9: Tricarboxylic Acid Cycle, Pyruvate Dehydrogenase Complex5and oxidative phosphorylation2000Chapter 10: Gluconeogenesis2000Chapter 11: Glycogen Metabolism2000Chapter 12: Metabolism of Monosaccharides and DisaccharidesChapter13:PentosePhosphatePathway andNicotinamide2000AdenineDinucleotidePhosphateChapter 14:Glycosaminoglycans, Proteoglycans, and2000GlycoproteinsUNIT Ill:Lipid Metabolism0010Chapter 15:Dietary Lipids MetabolismChapter 16: Fatty Acid, Ketone Body, and Triacylglycerol5000MetabolismChapter 17: Phospholipid, Glycosphingolipid, and Eicosanoid0400Metabolism4000Chapter 18: Cholesterol, Lipoprotein, and Steroid MetabolismUNIT IV: Nitrogen Metabolism4000Chapter19:AminoAcids:DisposalofNitrogen3000Chapter20:AminoAcidDegradationand Synthesis2000Chapter 21:Conversion of Amino Acids to Specialized Products3000Chapter 22: Nucleotide MetabolismUNIT V: Integration of Metabolism2000Chapter 23: Metabolic Effects of Insulin and Glucagon4000Chapter 24: The Feed-Fast Cycle2000Chapter 25: Diabetes Mellitus2000Chapter 26: Nutrition1
1 教学时数分配表（共 72 学时） 教学内容 理论 自学 实验 示教 备注 Introduction 1 0 0 0 UNIT I: Protein Structure and Function Chapter 1 : Amino Acids 1 0 0 0 Chapter 2: Structure of Proteins 3 0 0 0 Chapter 3: Globular Proteins 3 0 0 0 Chapter 4: Enzymes 4 0 0 0 Chapter 5: Vitamins 2 0 0 0 UNIT II: Bioenergetics and Carbohydrate Metabolism Chapter 6: Bioenergetics 3 0 0 0 Chapter 7: Introduction to Carbohydrates 1 0 0 0 Chapter 8: Introduction to Metabolism and Glycolysis 3 0 0 0 Chapter 9: Tricarboxylic Acid Cycle, Pyruvate Dehydrogenase Complex and oxidative phosphorylation 5 0 0 0 Chapter 10: Gluconeogenesis 2 0 0 0 Chapter 11: Glycogen Metabolism 2 0 0 0 Chapter 12: Metabolism of Monosaccharides and Disaccharides 2 0 0 0 Chapter 13: Pentose Phosphate Pathway and Nicotinamide Adenine Dinucleotide Phosphate 2 0 0 0 Chapter 14: Glycosaminoglycans, Proteoglycans, and Glycoproteins 2 0 0 0 UNIT III: Lipid Metabolism Chapter 15: Dietary Lipids Metabolism 1 0 0 0 Chapter 16: Fatty Acid, Ketone Body, and Triacylglycerol Metabolism 5 0 0 0 Chapter 17: Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism 4 0 0 0 Chapter 18: Cholesterol, Lipoprotein, and Steroid Metabolism 4 0 0 0 UNIT IV: Nitrogen Metabolism Chapter 19: Amino Acids: Disposal of Nitrogen 4 0 0 0 Chapter 20: Amino Acid Degradation and Synthesis 3 0 0 0 Chapter 21 : Conversion of Amino Acids to Specialized Products 2 0 0 0 Chapter 22: Nucleotide Metabolism 3 0 0 0 UNIT V: Integration of Metabolism Chapter 23: Metabolic Effects of Insulin and Glucagon 2 0 0 0 Chapter 24: The Feed-Fast Cycle 4 0 0 0 Chapter 25: Diabetes Mellitus 2 0 0 0 Chapter 26: Nutrition 2 0 0 0
合计72000Appendix: Clinical Case studyI INTEGRATIVE CASES1.1 Chest PainMyocardial infarction, LDL, cholesterol,HMG-CoA, Km1.2Severe Fasting HypoglycemiaGlucose 6-phosphatase deficiency (glycogen storagedisease [GSD]type Ia, von Gierke disease)VitD, purine-urate, triglyceride, membrane protein biosynthesis1.3Hyperglycemia &HyperketonemiaTypeI diabetes,Diabetic ketoacidosisII. FOCUSED CASES2.1 Microcytic AnemiaHb,Anemia withbeta-Thalassemia Minor,allele-specific oligonucleotide(ASO)hybridizationtedlnique useful in the diagnosis,2.6Dark Urine &YellowScleraeGlucose6-phosphatedehydrogenase(G6PD)defliciency,anX-Ilnked disorderthatcauseshemolysis (RBC lysis)2.7Joint painJoint Pain with Gout2.9 Elevated AmmoniaHyperammonemia with a Urea CycleDefectUNITIProteinStructureandFunctionChapter 1 Amino Acids[Aims & Requirements]1.Befamiliarwiththeclassificationof20aminoacids commonlyfound inproteins2.Befamiliar with thefeatures of some specific amino acids3.Understandtheconceptofpl (isoelectricpoint)[Main Contents]1.Overview2.Structureand classification ofAAs3.AcidicandbasicpropertiesofAAs[Key & Difficult Points]Classificationof20aminoacids.Conceptofpl(isoelectricpoint)[Teaching Methods]1.LecturewithMultimedia2.Group discussionChapter 2 Structure of Proteins[Aims&Requirements1.Understand the concepts of peptide bond,peptide unit, denaturation, and renaturation2.Be familiar with the molecular structure of proteins and protein physicochemical properties3. Understand the structure-function relationships of proteins4. Be aware of the concepts ofmotif and domain[Main Contents]1.Overview2
2 合计 72 0 0 0 Appendix: Clinical Case study I. INTEGRATIVE CASES 1.1 Chest Pain Myocardial infarction, LDL, cholesterol, HMG-CoA, Km 1.2 Severe Fasting Hypoglycemia Glucose 6-phosphatase deficiency (glycogen storage disease [GSD] type Ia, von Gierke disease), VitD, purine-urate, triglyceride, membrane protein biosynthesis 1.3 Hyperglycemia & Hyperketonemia Type I diabetes, Diabetic ketoacidosis II. FOCUSED CASES 2.1 Microcytic Anemia Hb, Anemia with beta-Thalassemia Minor, allele-specific oligonucleotide (ASO) hybridization tedlnique useful in the diagnosis, 2.6 Dark Urine & Yellow Sclerae Glucose 6-phosphate dehydrogenase ( G6PD) defliciency, an X·llnked disorder that causes hemolysis (RBC lysis) 2.7 Joint pain Joint Pain with Gout 2.9 Elevated Ammonia Hyperammonemia with a Urea Cycle Defect UNIT I Protein Structure and Function Chapter 1 Amino Acids [Aims & Requirements] 1. Be familiar with the classification of 20 amino acids commonly found in proteins 2. Be familiar with the features of some specific amino acids 3. Understand the concept of pI (isoelectric point) [Main Contents] 1. Overview 2. Structure and classification of AAs 3. Acidic and basic properties of AAs [Key & Difficult Points] Classification of 20 amino acids. Concept of pI (isoelectric point). [Teaching Methods] 1. Lecture with Multimedia 2. Group discussion Chapter 2 Structure of Proteins [Aims & Requirements] 1. Understand the concepts of peptide bond, peptide unit, denaturation, and renaturation 2. Be familiar with the molecular structure of proteins and protein physicochemical properties 3. Understand the structure-function relationships of proteins 4. Be aware of the concepts of motif and domain [Main Contents] 1. Overview
2.Primarystructureof proteins3. Secondary structure of proteins4. Tertiary structure of globular proteins5. Quaternary structure of protein6. Protein misfolding[Key and Difficult Points]Structure-function relationships of protein[Teaching Methods]1. Lecture with Multimedia2. Group discussion3. Case StudyChapter 3 Globular Proteins[Aims & Requirements]1. Be familiar with the structure and function of myoglobin2.Be familiar with the structure and function of hemoglobin3.BefamiliarwiththeO2-dissociationcurvesof MbandHb4.Understand the concepts of allostetic effect and bohr effect.5.Understand the allosteric effects of Hbby pO2,pH,pCO2,and 2,3-BPG6.Beawareofminorhemoglobins7.Befamiliarwiththemolecularmechanisms of sicklecell anemia8.Befamiliarwiththemolecularmechanisms of thalassemia[Main Contents]1.Overview2. Globular Hemeproteins3. Hemoglobinopathies[Key&Difficult Points]1. Allosteric effects of Hb by pO2, pH, pCO2, and2,3-BPG2.Molecularmechanisms of sickle cellanemia[Teaching Methods]1.Lecture withMultimedia2.Group discussionChapter 4Enzymes[Aims & Requirements]1.Be aware of enzyme nomenclature2. Be familiar with the enzyme properties3.Be familiar withhow enzymes work4. Be familiar with factors affecting reaction velocity and understand how they affect5.Understand the types and mechanisms of enzyme inhibition6. Understand the types and mechanisms of enzyme regulation7.Be familiar with the application of enzymes in clinical diagnosis[Main Contents]1.Overview2. Nomenclature3
3 2. Primary structure of proteins 3. Secondary structure of proteins 4. Tertiary structure of globular proteins 5. Quaternary structure of protein 6. Protein misfolding [Key and Difficult Points] Structure-function relationships of protein [Teaching Methods] 1. Lecture with Multimedia 2. Group discussion 3. Case Study Chapter 3 Globular Proteins [Aims & Requirements] 1. Be familiar with the structure and function of myoglobin 2. Be familiar with the structure and function of hemoglobin 3. Be familiar with the O2-dissociation curves of Mb and Hb 4. Understand the concepts of allostetic effect and bohr effect. 5. Understand the allosteric effects of Hb by pO2, pH, pCO2, and 2,3-BPG 6. Be aware of minor hemoglobins 7. Be familiar with the molecular mechanisms of sickle cell anemia 8. Be familiar with the molecular mechanisms of thalassemia [Main Contents] 1. Overview 2. Globular Hemeproteins 3. Hemoglobinopathies [Key & Difficult Points] 1. Allosteric effects of Hb by pO2, pH, pCO2, and 2,3-BPG. 2. Molecular mechanisms of sickle cell anemia [Teaching Methods] 1. Lecture with Multimedia 2. Group discussion Chapter 4 Enzymes [Aims & Requirements] 1. Be aware of enzyme nomenclature 2. Be familiar with the enzyme properties 3. Be familiar with how enzymes work 4. Be familiar with factors affecting reaction velocity and understand how they affect 5.Understand the types and mechanisms of enzyme inhibition 6. Understand the types and mechanisms of enzyme regulation 7. Be familiar with the application of enzymes in clinical diagnosis [Main Contents] 1. Overview 2. Nomenclature
3. Properties4.HowEnzymesWork5.Factors Affecting Reaction Velocity6. Michaelis-Menten Kinetics7. Inhibition of Enzyme Activity8.Regulationof EnzymeActivity9. Enzymes in Clinical Diagnosis[Key& Difficult Points]1.Factors Affecting Reaction Velocity2. Michaelis-Menten Kinetics3.Inhibition ofEnzyme Activity4,RegulationofEnzymeActivity[Teaching Methods]1.Lecture with Multimedia2.Group discussionChapter 5Vitamins[Aims & Requirements]1.Befamiliarwiththeconceptandclassificationofvitamins2.Be familiar withthe activeform, function, anddeficiency of Folic acid3.Befamiliarwiththeactiveform,function,anddeficiency ofCobalamin(VitB12)4.Be familiar with the active form,function, and deficiency of Pyridoxine (Vit B6)5.Befamiliar with the activeform,function,and deficiency ofThiamine(VitB1)6. Be familiar with the activeform, function, and deficiency of Niacin7. Be familiar with the active form, function, and deficiency of Riboflavin (Vit B2)8. Be familiar with the active form,function, and deficiency of Biotin9.Befamiliarwiththe activeform,function, anddeficiency of Pantothenic acid[Main Contents]1.Overview2.Folic acid3. Cobalamin (Vit B12)4. Pyridoxine (Vit B6)5. Thiamine (Vit BI)6. Niacin7. Riboflavin (Vit B2)8. Biotin9.Pantothenic acid[Key&DifficultPointsClassification of20 aminoacids.Concept ofpl (isoelectricpoint)[Teaching Methods]1.Lecture with Multimedia2. Group discussionUNIT 2Bioenergetics and Carbohydrate MetabolismChapter 6Bioenergetics4
4 3. Properties 4. How Enzymes Work 5. Factors Affecting Reaction Velocity 6. Michaelis-Menten Kinetics 7. Inhibition of Enzyme Activity 8. Regulation of Enzyme Activity 9. Enzymes in Clinical Diagnosis [Key & Difficult Points] 1. Factors Affecting Reaction Velocity 2. Michaelis-Menten Kinetics 3. Inhibition of Enzyme Activity 4. Regulation of Enzyme Activity [Teaching Methods] 1. Lecture with Multimedia 2. Group discussion Chapter 5 Vitamins [Aims & Requirements] 1. Be familiar with the concept and classification of vitamins 2. Be familiar with the active form, function, and deficiency of Folic acid 3. Be familiar with the active form, function, and deficiency of Cobalamin (Vit B12) 4. Be familiar with the active form, function, and deficiency of Pyridoxine (Vit B6) 5. Be familiar with the active form, function, and deficiency of Thiamine (Vit B1) 6. Be familiar with the active form, function, and deficiency of Niacin 7. Be familiar with the active form, function, and deficiency of Riboflavin (Vit B2) 8. Be familiar with the active form, function, and deficiency of Biotin 9. Be familiar with the active form, function, and deficiency of Pantothenic acid [Main Contents] 1. Overview 2. Folic acid 3. Cobalamin (Vit B12) 4. Pyridoxine (Vit B6) 5. Thiamine (Vit B1) 6. Niacin 7. Riboflavin (Vit B2) 8. Biotin 9. Pantothenic acid [Key & Difficult Points] Classification of 20 amino acids. Concept of pI (isoelectric point). [Teaching Methods] 1. Lecture with Multimedia 2. Group discussion UNIT 2 Bioenergetics and Carbohydrate Metabolism Chapter 6 Bioenergetics