Physiology -1812760 Course Sy1labus Course Number:18121760 Prerequisites:Human anatomy and histology Credits (hours per week,Lecture/Practical):7 (5-4) Tear:Ist year 2nd semester COURSE DESCRIPTION: This course is designed to provide students with a basic understanding of the mechanisns by which the normal human body functions.Specifically,students will be taught how the organ systens operate and interact to mintain honeostasis,how the systems change from birth to senescence,and how they respond to internal and external events.Through experience in the laboratory,students will be given the opportunity to study physiological phenonena,develop skills in the analysis and interpretation of data,and learn to distinguish between mormal and abnormal findings. OBJECTIVES: Knowledge At the end of the course the student will be able to: 1.explain the normal functioning of all the organ systems of the body and their interactions. 2.narrate the contribution of each organ systen to the maintenance of horeostasis. 3.elucidate the physiological aspects of norml growth and developaent. 4.describe the physiological responses and adaptatioas to emvironmental stresses. 5.list the physfological principles underlying the pathogemesis and treatment of disease. Skills At the end of the course the student will be able to:
Physiology -1812760 Course Syllabus Course Number: 18121760 Prerequisites: Human anatomy and histology Credits (hours per week, Lecture/Practical): 7 (5-4) Year: 1st year 2nd semester COURSE DESCRIPTION: This course is designed to provide students with a basic understanding of the mechanisms by which the normal human body functions. Specifically, students will be taught how the organ systems operate and interact to maintain homeostasis, how the systems change from birth to senescence, and how they respond to internal and external events. Through experience in the laboratory, students will be given the opportunity to study physiological phenomena, develop skills in the analysis and interpretation of data, and learn to distinguish between normal and abnormal findings. OBJECTIVES: Knowledge At the end of the course the student will be able to: 1. explain the normal functioning of all the organ systems of the body and their interactions. 2. narrate the contribution of each organ system to the maintenance of homeostasis. 3. elucidate the physiological aspects of normal growth and development. 4. describe the physiological responses and adaptations to environmental stresses. 5. list the physiological principles underlying the pathogenesis and treatment of disease. Skills At the end of the course the student will be able to:
1.perform experinents designed either primarily for the study of physiological phenonena or for assessment of function. 2 analyse and interpret experinental/investigative data critically. 3.distinguish between normal and abnormal data derived as a result of tests which he/she has performed and observed in the laboratory. COURSE CONTENT: Lectures The lecture content is orgamized around the textbook.Fander's Mon Physiology:The Mechanises of Body function (10th edition)as follows: General introduction:honeosts8is 5 hr 1.Introduction 2.Bacostasis 3.Control systems 4.Erolution 5.Medically-related exanples Cellular physiology:receptors,excitable cells12 hr 1.Cell membrane:properties 2.Cell menbrane:perneability 3.Cell sonbrane:transport 4.Bioelectricity 5.Resting meabrane potential 6.Action potential 7.Excitation-contraction coupling &.Cardiac即scle 9.Skeletal nuscle 10.Snooth ruscle 11.Receptors 12.Medically-related examples Cardiovascular systea 10 hr
1. perform experiments designed either primarily for the study of physiological phenomena or for assessment of function. 2. analyse and interpret experimental/investigative data critically. 3. distinguish between normal and abnormal data derived as a result of tests which he/she has performed and observed in the laboratory. COURSE CONTENT: Lectures The lecture content is organized around the textbook, Vander’s Human Physiology: The Mechanisms of Body Function (10th edition) as follows: General introduction: homeostasis 5 hr 1. Introduction 2. Homeostasis 3. Control systems 4. Evolution 5. Medically-related examples Cellular physiology: receptors, excitable cells12 hr 1. Cell membrane: properties 2. Cell membrane: permeability 3. Cell membrane: transport 4. Bioelectricity 5. Resting membrane potential 6. Action potential 7. Excitation-contraction coupling 8. Cardiac muscle 9. Skeletal muscle 10. Smooth muscle 11. Receptors 12. Medically-related examples Cardiovascular system 10 hr
1.Introduction 2.Blood 3.Beart 4.Electrocardiogram 5.Cardiac cyele 6.Neural regulation of cardiae function 7.Intrinsic regulation of cardiac function 8.Cardiac output 9.Bemodynanics 10.Special circulations Endocrine systeml0 hr 1.Introduetion 2.Hypothalanic comtrol system 3.Anterior pituitary hormones 4.Posterior pituitary hormones 5.Thyroid:control of functions 6.Actions of thyroid hormones 7.Adrenals 8.Functions of cortisol 9.Cortisol stress 10.Endocrine control of growth Gastrointestinal systen 8 hr 1.Introduetion 2.Chewing swallowing 3.Gastric secretion 4.Regulation of aastric secretion 5.Biliary pancreatic secretions 6.Colon 7.Nutrition I &.utritio始II
1. Introduction 2. Blood 3. Heart 4. Electrocardiogram 5. Cardiac cycle 6. Neural regulation of cardiac function 7. Intrinsic regulation of cardiac function 8. Cardiac output 9. Hemodynamics 10. Special circulations Endocrine system10 hr 1. Introduction 2. Hypothalamic control system 3. Anterior pituitary hormones 4. Posterior pituitary hormones 5. Thyroid: control of functions 6. Actions of thyroid hormones 7. Adrenals 8. Functions of cortisol 9. Cortisol & stress 10. Endocrine control of growth Gastrointestinal system 8 hr 1. Introduction 2. Chewing & swallowing 3. Gastric secretion 4. Regulation of gastric secretion 5. Biliary & pancreatic secretions 6. Colon 7. Nutrition I 8. Nutrition II
Nervous syste 10 hr 1.Introduction 2.Synaptle transmission 3.Neurotransaitters receptors 4.Sensory coding 5.Sensory perception 6.Pain 7.Control of pain 8.Motor systems 9.Reflexes 10.Voluntary novenents Respiratory systen8 hr 1.Introduetion 2.Limng volunes capacities 3.Mechanics of veatilation 4.Ventilation-perfusion ratio &Gas exchange【 6.Gas exchange II 7.Neural/chemical regulation of respiration 8.Artificial respiration Urogenital system12 hr 1.Introduction to reproductive systens 2.Hypothalanic-pituitary-gonadal axis 3.Male reproductive physiology 4.Female reproductive physiology 5.Puberty 6.Pregnaney 7.Introduction to renal system 8.Bemodynanics A glorerular filtration 9.Renal tubule functions I
Nervous system 10 hr 1. Introduction 2. Synaptic transmission 3. Neurotransmitters & receptors 4. Sensory coding 5. Sensory perception 6. Pain 7. Control of pain 8. Motor systems 9. Reflexes 10. Voluntary movements Respiratory system8 hr 1. Introduction 2. Lung volumes & capacities 3. Mechanics of ventilation 4. Ventilation-perfusion ratio 5. Gas exchange I 6. Gas exchange II 7. Neural/chemical regulation of respiration 8. Artificial respiration Urogenital system12 hr 1. Introduction to reproductive systems 2. Hypothalamic-pituitary-gonadal axis 3. Male reproductive physiology 4. Female reproductive physiology 5. Puberty 6. Pregnancy 7. Introduction to renal system 8. Hemodynamics & glomerular filtration 9. Renal tubule functions I
10.Renal tubule functions II 11.Regulation of renal functions 12.Micturition Integrated responses to internal/external change 5 hr 1.Autononic nervous system 2.Work physiology 2 Life at high altitude 4.Beat and cold 5.Growth.developeent and senescence Practicals The laboratory-based contemt is designed to complement the lectures. Content Hours 1.Introduction to Experinental Physiology 4 2.Use of data acquisition system in experimental physiology 1.Nerve preparation -sciatic nerve of toad 4 2.Measurement of compound action potential in sciatic nerve 3.Measurement of nerve inpulse velocity 1.Nerve-muscle preparation sciatic nerve gastrocnenius 4 muscle of toad 2.Recording phases of ruscle contraction 3.Effects of stimulation with different intensities and frequencies on ruscle 1.Determination of hemoglobin concentration of blood 4 2.RBC.VBC platelet count 3.Determination of MCV,MCH.MCHC 4.Determination of PCV 5.Hemolysis and fragility test 1.Spirometry:lung volunes and capacities 4 2.Recording of chest movements by a stethograph
10. Renal tubule functions II 11. Regulation of renal functions 12. Micturition Integrated responses to internal/external change 5 hr 1. Autonomic nervous system 2. Work physiology 3. Life at high altitude 4. Heat and cold 5. Growth, development and senescence Practicals The laboratory-based content is designed to complement the lectures. Content Hours 1. Introduction to Experimental Physiology 2. Use of data acquisition system in experimental physiology 4 1. Nerve preparation - sciatic nerve of toad 2. Measurement of compound action potential in sciatic nerve 3. Measurement of nerve impulse velocity 4 1. Nerve-muscle preparation – sciatic nerve & gastrocnemius muscle of toad 2. Recording phases of muscle contraction 3. Effects of stimulation with different intensities and frequencies on muscle 4 1. Determination of hemoglobin concentration of blood 2. RBC, WBC & platelet count 3. Determination of MCV, MCH, MCHC 4. Determination of PCV 5. Hemolysis and fragility test 4 1. Spirometry: lung volumes and capacities 2. Recording of chest movements by a stethograph 4
Virtual Experiment:Respiratory regulation 4 Movement of isolated segment of mammalian small intestine 4 1.Auscultation of heart sounds and BP measurenent 4 2.Effect of exercise on arterial blood pressure 1.Virtual Experiment:Effects of ions and drugs on isolated 4 perfused heart 2.ECG Regulation of arterial blood pressure 4 1.Routine urine examination 2.Virtual Experiment:Regulation of urine formation Effect of insulin on plasn glucose level 4 Yideo:Labor and Delivery 4 Exanination of sensory systems 4 Examination of cranial nerves 1.EEG EMG 4 2.Reflex testing STRUCTURE: The course comprises 80 hr of lectures and 64 hr of practicals. Two lecture sessions,one for 2 hr and one for 3 hr.will be beld each week. One weekly 4 hr practical session will be held. Two tests (1 hr each)will be given before the final examination.at about the sixth (multiple-choice and short-answer questions)and twelfth weeks (essay questions). The final examination (2 hr)will contain a mixture of the above types of questions. ORGANIZATION: Each session will be offered to the entire class
Virtual Experiment: Respiratory regulation 4 Movement of isolated segment of mammalian small intestine 4 1. Auscultation of heart sounds and BP measurement 2. Effect of exercise on arterial blood pressure 4 1. Virtual Experiment: Effects of ions and drugs on isolated perfused heart 2. ECG 4 Regulation of arterial blood pressure 4 1. Routine urine examination 2. Virtual Experiment: Regulation of urine formation 4 Effect of insulin on plasma glucose level 4 Video: Labor and Delivery 4 Examination of sensory systems 4 Examination of cranial nerves 4 1. EEG & EMG 2. Reflex testing 4 STRUCTURE: The course comprises 80 hr of lectures and 64 hr of practicals. Two lecture sessions, one for 2 hr and one for 3 hr, will be held each week. One weekly 4 hr practical session will be held. Two tests (1 hr each) will be given before the final examination, at about the sixth (multiple-choice and short-answer questions) and twelfth weeks (essay questions). The final examination (2 hr) will contain a mixture of the above types of questions. ORGANIZATION: Each session will be offered to the entire class
An assistant vill act as liaison between students and teachers,and will be responsible for taking attendance,collecting exan papers.and related matters. EVALUATION: Students'performance will he evaluated on the basis of attendance at lectures and participation in practicals (58),practical reports (15%),scores on tests (20%) and scores on the final examination (60%). RECOMMENDED TEXTBOOK: Widnaier EP.Raff H.Strang KT (2006)Vander's Buan Physiology:The Mechanisas of Body Funetion.Tenth Edition.McGraw-Hill. SUPPLEMENTARY READING: Levy MN.Koeppen BMl,Stanton BA (2005)Berne Levy,Principles of Physiology. Fourth Edition.Mosby. TEACHING TEAM: Faculty: Prof.IC Bruce Te1:8820g292 Email:icbruceez ju.edu.cn Bn 541.Block C.Research Building.School of Medicine,Zijingang Campus Prof.Q Xia Te1:88208252 Enail:xiaqiangez ju.edu.cn Rn 518.Block C.Research Building.School of Wedicine.Zijingang Campus Prof.TM Vong Enail:wongtaknehkucc.hku.hk Dr.ISS Hang Enail:isahelssehkucc.hku.hk Dr.YY Chen Enail:bchenyyezju.edu.cn Dr.LL Wang Email:wanglinlinezju.edu.cn
An assistant will act as liaison between students and teachers, and will be responsible for taking attendance, collecting exam papers, and related matters. EVALUATION: Students’ performance will be evaluated on the basis of attendance at lectures and participation in practicals (5%), practical reports (15%), scores on tests (20%) and scores on the final examination (60%). RECOMMENDED TEXTBOOK: Widmaier EP, Raff H, Strang KT (2006) Vander’s Human Physiology: The Mechanisms of Body Function, Tenth Edition. McGraw-Hill. SUPPLEMENTARY READING: Levy MN, Koeppen BM, Stanton BA (2005) Berne & Levy, Principles of Physiology, Fourth Edition. Mosby. TEACHING TEAM: Faculty: Prof. IC Bruce Tel: 88208292 Email: icbruce@zju.edu.cn Rm 541, Block C, Research Building, School of Medicine, Zijingang Campus Prof. Q Xia Tel: 88208252 Email: xiaqiang@zju.edu.cn Rm 518, Block C, Research Building, School of Medicine, Zijingang Campus Prof. TM Wong Email: wongtakm@hkucc.hku.hk Dr. ISS Hwang Email: isabelss@hkucc.hku.hk Dr. YY Chen Email: bchenyy@zju.edu.cn Dr. LL Wang Email: wanglinlin@zju.edu.cn
Dr.YQ Yu Enail:yanqinyuezju.edu.cn Dr.X Zhang Enail:xzhang1973@yahoo.com Assistant: Dr.H顶Liang Te1:88208159 Enail:hwliangez ju.edu.cn Rn 521.Block C.Research Building.School of Medicine,Zijingang Carpus
Dr. YQ Yu Email: yanqinyu@zju.edu.cn Dr. X Zhang Email: xzhang1973@yahoo.com Assistant: Dr. HW Liang Tel: 88208159 Email: hwliang@zju.edu.cn Rm 521, Block C, Research Building, School of Medicine, Zijingang Campus